Journal club

Journal club meetings are on Mondays at 2-3 pm through video conference.

April 21, 2021
Predicting new protein conformations from molecular dynamics simulation conformational landscapes and machine learning

Yiming Jin, Linux O. Johannissen, Sam Hay: Prediction new protein conformations from molecular dynamics simulation conformational landscapes and machine learning. Proteins (2021)

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presented by Michael

April 21, 2021
MSA Transformer

Rao R, Liu J, Verkuil R, Meier J, Canny JF, Abbeel P, et al. MSA Transformer. bioRxiv. 2021.

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presented by Lim

April 14, 2021
Protein sequence design by conformational landscape optimization

Norn et al., (2021) PNAS

Abstract | PDF | SI

Presented by Giacomo

April 7, 2021
FtsZ-Induced shape transformation of coacervates

Fanalista, F., Deshpande, S., Lau, A., Pawlik, G., & Dekker, C. (2018). Advanced Biosystems2(9), 1800136. https://doi.org/10.1002/adbi.201800136

Abstract PDF | SI

presented by Gilberto

March 24, 2021
Mechanistic basis for ubiquitin modulation of a protein energy landscape

Carroll, E.C., Latorraca, N.R., Lindner, J.M., Maguire, B.C., Pelton, J.G., and Marqusee, S. Proc. Natl. Acad. Sci. U.S.A. (2021).

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presented by Lim

March 17, 2021
Discovery of a hidden transient state in all bromodomain families

Raich et al., (2021) PNAS

Abstract | PDF | SI

Presented by Giacomo

March 3, 2021
Spontaneous driving forces give rise to protein−RNA condensates with coexisting phases and complex material properties

Boeynaems, S., Holehouse, A. S., Weinhardt, V., et al. (2019). PNAS, 116(16), 7889–7898. https://doi.org/10.1073/pnas.1821038116

Abstract PDF | SI

presented by Gilberto

February 17, 2021
Extraction of protein dynamics information from cryo-EM maps using deep learning

Matsumoto et al., Nature Machine Intelligence (2021).

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presented by Lim

February 10, 2021
Deciphering interaction fingerprints from protein molecular surfaces using geometric deep learning

Gainza et al., (2020) Nature Methods

Abstract | PDF | SI

Presented by Giacomo

February 3, 2021
Lysine/RNA-interactions drive and regulate biomolecular condensation

Ukmar-Godec, T., Hutten, S., Grieshop, M.P. et al. Nat Commun 10, 2909 (2019) https://doi.org/10.1038/s41467-019-10792-y

Abstract PDF | SI

presented by Gilberto

January 27, 2021
Tensor field networks: Rotation- and translation-equivariant neural networks for 3D point clouds

Thomas et al., arXiv (2018).

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presented by Lim

January 20, 2021
Fast and effective protein model refinement by deep graph neural networks

Xiaoyang Jing and Jinbo Xu (2020) bioRxiv,

January 13, 2021
Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization

Sanders, D. W., et al (2020) Cell181(2), 306-324.e28, doi.org/10.1016/j.cell.2020.03.050

Abstract PDF | SI

presented by Gilberto

January 6, 2021
Genetic interaction mapping informs integrative structure determination of protein complexes

Braberg et al., Science (2020).

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presented by Lim

December 16, 2020
Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations

Zheng, W., et al. (2020). JPC B, acs.jpcb.0c10489

Abstract PDF | SI

presented by Gilberto

December 9, 2020
Refining All-Atom Protein Force Fields for Polar-Rich, Prion-like, Low-Complexity Intrinsically Disordered Proteins

W. S. Tang, N. L. Fawzi, and J. Mittal
J. Phys. Chem. B 2020, 124, 9505−9512

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presented by Bercem

November 23, 2020
Chasing coevolutionary signals in intrinsically disordered proteins complexes

Iserte, J.A., et al., Scientific reports (2020).

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presented by Lim

November 16, 2020
Phase transition of RNA−protein complexes into ordered hollow condensates

Alshareedah, I. et al. PNAS, 117, 15650–15658 (2020) 

Abstract PDF | SI

presented by Gilberto

November 9, 2020
Phase separation at the nanoscale quantified by dcFCCS

S. Peng, W. Li, Y. Yao, W. Xing, P. Li, and C. Chen

presented by Bercem

November 2, 2020
Single Layers of Attention Suffice to Predict Protein Contacts

Anonymous authors, Under review as a conference paper at ICLR 2021.

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presented by Lim