| Tuesday | 1/13 | 3-3:50 pm | in BCH 502 |
| Thursdays | 1/22-4/30 | 2:30 - 4 pm | in BCH 502 |
| 1/13 | Tuesday | 3-3:50 pm | Feig: Course introduction |
| 1/22 | Thursday | 3-4 pm | Wedemeyer: Introduction to protein and nucleic acid structure |
| 1/29 | Thursday | 2:30-4 pm | Ziru Li: Protein folding/function #1 (Wedemeyer) Annual Review of Biochemistry 77, 363-382 (2008) (background) PNAS 104, 14664-14669 (2007) |
| 2/5 | Thursday | 2:30-4 pm | Fadhiru Kamba: Protein folding/function #2 (Wedemeyer) Nature 453, 190-195 (2008) |
| 2/12 | Thursday | 2:30-4 pm | Maryam Sayadi: Membrane proteins #1: P-type ATPases (Feig) Nature 450, 1036-1042 (2007) Nature 450, 1043-1049 (2007) |
| 2/19 | Thursday | 2:30-4 pm | Afra Panahi: Membrane proteins #2: Potassium channel (Feig) Nature 414, 73-77 (2001) PNAS 104, 9260-9265 (2007) Biophysical Journal 95, 5062-5072 (2008) |
| 2/26 | Thursday | 2:30-4 pm | Jifeng Wang: Metalloenzymes #1: Amidohydrolases (Hausinger) Biochemistry 44, 6383-6391 (2005) (background) Journal of Molecular Biology 379, 1017-1028 (2008) |
| 3/5 | Thursday | 2:30-4 pm | Sean Law: Metalloenzymes #2: 2-oxoglutarate oxygenases (Hausinger) Journal of Inorganic Biochemistry 100, 644-669 (2006) (background) Nature 452, 961-965 (2008) |
| 3/19 | Thursday | 2:30-4 pm | Rahul Banerjee: Enzyme dynamics and catalysis #1: Adenylate kinase (Yan) Chemical Reviews 106, 3055-3079 (2006) (background) Accounts of Chemical Research 41, 214-221 (2008) (background) Accounts of Chemical Research 41, 442-451 (2008) (background) Nature 450, 838-844 (2007) Nature 450, 913-916 (2007) |
| 3/26 | Thursday | 2:30-4 pm | Zhenwei Lu: Enzyme dynamics and catalysis #2: Triosephosphate isomerase (Yan) Chemical Reviews 106, 3055-3079 (2006) (background) Accounts of Chemical Research 41, 214-221 (2008) (background) Accounts of Chemical Research 41, 442-451 (2008) (background) Journal of Molecular Biology 368, 131-149 (2007) |
| 4/2 | Thursday | 2:30-4 pm | Patrick Ochieng: RNA structure and function #1: RNA folding (Hoogstraten) Nucleic Acids Research 36, 7088-7099 (2008) |
| 4/9 | Thursday | 2:30-4 pm | David Achila: RNA structure and function #2: RNA structure conservation (Hoogstraten) PLoS Biology 6, e96 (2008) |
| 4/16 | Thursday | 3-4 pm | Burton: RNA polymerase introduction |
| 4/23 | Thursday | 2:30-4 pm | Young-Moon Cho: RNA polymerase #1: Th. thermophilus X-ray structure (Burton) Nature 448, 157-163 (2007) Nature 448, 163-168 (2007) |
| 4/30 | Thursday | 2:30-4 pm | Michael King: RNA polymerase #2: E. coli single molecule dynamics (Burton) Nature 438, 460-465 (2005) |
In order to access class contents please connect from a campus computer or use a VPN connection.